Alimta and Cisplatin for Mesothelioma Treatments

Alimta and Cisplatin for Mesothelioma Treatments

The Food and Drugs Administration (FDA) have approved a combination of Alimta and Cisplatin for mesothelioma treatments, and other asbestos-associated diseases. The happens to be the first and only drug that is proved to help treat mesothelioma patients having any asbestos-associated disease approved by the FDA. Alimta was endorsed to be used with cisplatin, which is an approved chemotherapy agent good for malignant mesothelioma treatments, a deadly tumor of the lung lining, in mesothelioma patients who do not want to undergo surgery. One of the most lethal, painful, and devastating cancers a person can have is malignant mesothelioma. There are about 10,000 and 15,000 mesothelioma patients annually diagnosed with malignant mesothelioma in the world, and it increases greatly every year. Several people do not even know that they have malignant mesothelioma until it has gotten to a severe and advanced stage, whereby mesothelioma treatments options of surgery or radiation are not necessary. Alimta/cisplatin have really proven different. There was a comparison of this combination with cisplatin alone with around 448 mesothelioma patients from 19 nations – the biggest trial till date among mesothelioma patients having malignant mesothelioma. The results shown was that the total survival rate was 30% increased (about Alimta/cisplatin was used for 12.1 months compared to 9.3 months for cisplatin alone), and about 50.3% of mesothelioma patients undergoing Alimta/cisplatin treatment lived a year after in comparison to 38.0% who had only cisplatin. It has been proved for the first time that chemotherapy assists mesothelioma patients with malignant mesothelioma extend their lives, which is something to count for. Furthermore, research have also shown that there was an lung functionality improvement when the Alimto/Cisplatin was used, compared to the use of Cisplatin alone. However, there are some vital safety information. There are hematolgoic and non-hematologic side effects related to the use of Alimta, and they are anaemia, neutropenia, nausea, thrombocytopenia, vomiting, diarrhea, fatigue, pain, and skin rash. In order to decrease the severity of the side effects, all mesothelioma patients using Alimta must take a dose of folic acid and intramuscular injections of vitamin B12 daily.

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