Archive for the ‘Mesothelioma Treatment Option’ Category

Hot Chemotherapy as a Mesothelioma Treatment Option

Dr. David Sugarbaker, one of the country’s leading thoracic surgeons, discusses potential treatment options for mesothelioma patients. He is the Director of the International Mesothelioma Program and the Chief of Thoracic Surgery at Harvard’s Brigham and Women’s Hospital in Boston, Mass. Motley Rice LLC co-founder Joe Rice has been representing asbestos clients for decades and discusses mesothelioma treatment options that his clients may want to research.
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Asbestos Causes Mesothelioma in Lungs

Asbestos Causes Mesothelioma in Lungs

Asbestos is often called the silent killer. It is a carcinogen which causes cancer in mesothelial cells and due to this the cancer is named “Mesothelioma”. The mesothelial cells are the lining on internal organs like lungs, heart, abdomen etc. If mesothelioma develops in lungs, it is called pleural mesothelioma, if it develops in heart, it is called pericardial mesothelioma and in abdomen it is called peritonial mesothelioma.

This disease commonly occurs in lungs and the symptoms do not appear even after 40-45 years of inhalation of asbestos. People usually inhale fine fibers of asbestos at work places. It is used in many industries because of its durability, heat and fire resistant property by Metal plate workers, Decorators, Builders, Electricians, Carpenters, Gas fitters, Plumbers etc. Usually, men suffer with mesothelioma in lungs; women come in contact with asbestos while washing clothes of the people who have worked with asbestos.

Asbestos is found in many forms, but crocidolite, commonly known as blue asbestos is the most dangerous one. It is so because the fibers of blue asbestos are very fine. After inhalation, particles stick to the external lining of the lung known as pleura and cause cancer. The symptoms start with discomfort in the chest cavity, coughing, and eventual pain. Usually people don’t come to know in beginning and this lung cancer is diagnosed in its advanced stage and therefore, 20% patients survive up to 5 years after diagnosis.

Mesothelioma in lungs is incurable. The treatments used to cure this disease like Photodynamic Therapy, Photodynamic Therapy, Intensity Modulated Radiation Therapy, Gene Therapy, and Chemotherapy etc. can increase the life of the patient. Sometimes the affected lung, pericardium and half of the diaphragm are removed to extend the life of the patient.

Christen Scott is passionate about writing and love to write over different topics. These days she is writing about Mesothelioma.

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Pericardial Mesothelioma: a Concise Definition

Pericardial Mesothelioma: a Concise Definition

Mesothelioma is a cancer of the epithelium that lines the lungs, the abdomen, or the heart. Pericardial Mesothelioma is the cancer of the lining of the heart, known as the pericardium, hence the name pericardial mesothelioma.

This rare form of mesothelioma accounts for small percentage of all cases, roughly 5%. The pericardium has an extrememly important role as it protects the heart from any damage. Should an individual become afflicted with this cancer, they should take it very seriously and seek specialized medical attention. If left untreated during the early stages of diagnosis, it can become a terminal illness with a very low survival rate.

As with all forms of mesothelioma, pericardial mesothelioma is caused by inhaling asbestos. Those who are most at risk are construction workers and asbestos manufacturers. The wearing of a protective mask can help to minimize the inhalation of asbestos dust in to the lungs (since the asbestos fibres get lodged in the lungs). If you have noticed, the majority of workers aren’t properly protected when working on construction sites – even in industrialized nations such as the United States. One would expect to see otherwise, thinking that companies follow OSHA directives. That isn’t the case all the time.

During the middle of the 20th century (roughly between 1950-1970) asbestos was one of the most popular building materials, and scores of young men were exposed to it. Now, in the 21st century (some 50 years later – the latency period of pericardial mesothelioma), these young men who are now over 60 years of age are beginning to exhibit the symptoms of pericardial mesothelioma. As a result, multi-million dollar lawsuits are being filed against the companies that employed them.

The problem with pericardial mesothelioma is that its symptoms only start appearing in the cancer’s latest stages, making it even more difficult to treat. The main symptoms are shortness of breath, palpitations, chest pains and a persistent cough. Other symptoms of pericardial mesothelioma include nausea, weight loss and loss of appetite. Another problem with these symptoms is that they are similar to those of pneumonia (shortness of breath), and this tends to lead to the wrong treatment being administered to an individual afflicted with pericardial mesothelioma.

Treatment options for pericardial mesothelioma include chemotherapy, radiation, surgery, and dual therapy. The survival rate is extremely low, and it is important to stress that one’s chances of healing are increased should treatment commence in the early stages of diagnosis.

Having been a contributing author on the subject of

pericardial mesothelioma, Nkeno Kapya is our suggested

resource on the topic. You can visit his website for more


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Mesothelioma Lung Cancer remains a Challenge for Doctors

Mesothelioma Lung Cancer remains a Challenge for Doctors

Mesothelioma Lung Cancer is not very easy for doctors to diagnose. Though humankind has witnessed incredible advances in medical diagnosis technologies and methodologies, mesothelioma continues to stay a challenge for doctors. Thus, not every doctor can treat this disease. It calls for the service of a special set of doctors who are trained to handle mesothelioma cases.

Being a complicated disease, mesothelioma requires many differing types of treatment. Seeking the assistance of specialized doctors, each trained in precise fields or treatment, is the very best means Mesothelioma Treatment Options. Since there are various kinds of mesothelioma that affect different body parts, it is best if the disease is treated with a team. To start with, even before a patient is referred to the consultant team, the onus of suspecting the symptoms as related to cancer,eg mesothelioma, lies with the general practitioner.

Once the general practitioner refers the patient, the specialized team decides the future course of action. The 1st specialist in the team is a pulmonologist who is specifically trained to diagnose and treat conditions as well as diseases that are related to lung anomalies. This expert can competently handle cases of Mesothelioma Lung Cancer, lung cancer, bronchitis, asthma, emphysema, and COPD. The next expert in line is the thoracic surgeon, who focuses on undertaking surgery of the lungs, amongst others, and can deal with coronary disease, lung and intestinal cancers, and heart and lung surgery.

The medical oncologist is another trained physician who makes a speciality of treating cancer through chemical treatment. Even inside oncologists, there are many kinds of doctors who specialise in treating cancer. In contrast to the medical oncologist is the radiation oncologist, who treats cancer through radiation care, and the radiologist, who uses equipment such as x-rays, ultrasound, and scans to diagnose cancer.

An extra group of experts consists of pathologists who monitor and evaluate changes in the human cells in order to grasp the nature of the disease. Using body fluids and excretions, they identify the disease and its power. However unlike the other mesothelioma trained consultants, pathologists don’t immediately treat patients. Likewise, there are another experts who also don’t take part straight in the treatment process. These include the social employee and the respiratory specialist.

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Alimta and Cisplatin for Mesothelioma Treatments

Alimta and Cisplatin for Mesothelioma Treatments

The Food and Drugs Administration (FDA) have approved a combination of Alimta and Cisplatin for mesothelioma treatments, and other asbestos-associated diseases. The happens to be the first and only drug that is proved to help treat mesothelioma patients having any asbestos-associated disease approved by the FDA. Alimta was endorsed to be used with cisplatin, which is an approved chemotherapy agent good for malignant mesothelioma treatments, a deadly tumor of the lung lining, in mesothelioma patients who do not want to undergo surgery. One of the most lethal, painful, and devastating cancers a person can have is malignant mesothelioma. There are about 10,000 and 15,000 mesothelioma patients annually diagnosed with malignant mesothelioma in the world, and it increases greatly every year. Several people do not even know that they have malignant mesothelioma until it has gotten to a severe and advanced stage, whereby mesothelioma treatments options of surgery or radiation are not necessary. Alimta/cisplatin have really proven different. There was a comparison of this combination with cisplatin alone with around 448 mesothelioma patients from 19 nations – the biggest trial till date among mesothelioma patients having malignant mesothelioma. The results shown was that the total survival rate was 30% increased (about Alimta/cisplatin was used for 12.1 months compared to 9.3 months for cisplatin alone), and about 50.3% of mesothelioma patients undergoing Alimta/cisplatin treatment lived a year after in comparison to 38.0% who had only cisplatin. It has been proved for the first time that chemotherapy assists mesothelioma patients with malignant mesothelioma extend their lives, which is something to count for. Furthermore, research have also shown that there was an lung functionality improvement when the Alimto/Cisplatin was used, compared to the use of Cisplatin alone. However, there are some vital safety information. There are hematolgoic and non-hematologic side effects related to the use of Alimta, and they are anaemia, neutropenia, nausea, thrombocytopenia, vomiting, diarrhea, fatigue, pain, and skin rash. In order to decrease the severity of the side effects, all mesothelioma patients using Alimta must take a dose of folic acid and intramuscular injections of vitamin B12 daily.

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Mesothelioma Blood Test-Mesomark Test

Mesothelioma Blood Test-Mesomark Test

The reason for high death rates among mesothelioma patients is the aggressive nature of the disease and the inability to diagnose it until it is well advanced. Because mesothelioma symptoms do not show up until about 40-50 years after exposure to asbestos, most cases at the time of diagnosis have already reached Stage III or IV. As a result, mesothelioma treatment options are often more palliative than curative.

However, the ability to diagnose the disease at an earlier time would certainly result in a better prognosis for mesothelioma patients. That ability is now present in the form of a mesothelioma blood test known as Mesomark. Developed by Fujirebio Diagnostics Inc. of Malvern, Pennsylvania, a leader in the field of oncology testing, the test measures the amount of a particular biomarker in human serum.

The test was first released in Australia in March 2005 and distribution expanded to Europe just a few months later. Food and Drug Administration approval for the blood test was received nearly two years later in January 2007.

Testing for Mesothelioma

Mesomark is an easily performed blood test that uses an enzyme-linked immunosorbent assay to measure the amount of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker that is produced by mesothelioma cells, and this biomarker may be elevated in the serum of patients who have mesothelioma. The detection of the biomarker through a blood test can help attain an early diagnosis, resulting in more treatment options and a better prognosis for patients.

Mesomark is what is referred to as an in-vitro test. In this test, the blood that is drawn from the patient is sent to a laboratory to measure the level of SMRP. This is performed by using monoclonal antibodies that are known to specifically bind to SMRP. Measuring the amount of bound antibodies in the blood indicates the amount of SMRP, and certain levels indicate the presence of mesothelioma. In addition to detecting the presence of mesothelioma in yet-to-be-diagnosed patients, the Mesomark blood test may also be used to monitor the success of treatments in patients who have already been diagnosed with the disease.

These tests will also help determine the next course of treatment.

The Mesomark blood test has NOT yet been approved for the early diagnosis of mesothelioma.

This test has been approved as a Humanitarian Use Device (HUD), meaning that physicians must follow certain procedures to qualify their patients for testing. Once the physician is certified, informational brochures will be sent to be distributed to each applicable patient.

Those wishing to take part in Mesomark testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.

The costs associated with the Mesomark blood test may not be covered under health insurance, therefore, you may be required to pay all or part of the costs out of pocket. It is recommended that you check with your insurance carrier to determine whether coverage is available under your policy.

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