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Sirolimus – A Brand New Addition to Mesothelioma Treatment

Sirolimus – A Brand New Addition to Mesothelioma Treatment

Mesothelioma treatment improved with addition to Sirolimus treatment. This is wonderful news for mesothelioma patient because of its anti-proliferative effects; sirolimus is now being looked at for the treatment of malignant mesothelioma and a number of other cancers.

After being diagnosed with mesothelioma it is natural to experience a whirlwind of emotions. This lethal disease can definitely turn your life upside down, but rests assure that researchers are working night and day to find a cure for you!

Researchers at the Boston women’s hospital report that the immune suppressant drug called Sirlimus is an effective mesothelioma treatment. According to the researchers working at Brigham and Women’s Hospital in Boston they saw greater success when using sirolimus along with cisplatin than they did when using cisplatin alone.

What Is Sirolimus?

Sirolimus also known as rapamycin is an immunosuppressant drug which is typically used to prevent rejection of organ transplantations especially in kidney transplants. Sirolimus has an anti-proliferative effect which makes it an effective treatment option for mesothelioma.

Benefits of Sirolimus

It is believed that the benefits of sirolimus could make it easier to treat certain cancers. Sirolimus acts as an inhibitor in the development of certain proteins that affects the cell survival and cell growth among others. The researchers also stated that upon observation of combination of sirolimus and cisplatin “Sirolimus appears to enhance the cytotoxicity of cisplatin in malignant pleural mesothelioma cell lines through the mammalian target rapamycin pathway. These results provide a basis for the clinical evaluation of combined sirolimus and cisplatin chemotherapy in malignant pleural mesothelioma.”

Precautions & Warnings When Taking Sirolimus

According to research, before taking sirolimus you should follow these guidelines:

Let your doctor know if your are allergic to any medication Give your doctor a list of medication (prescription or non prescription) including vitamins nutritional supplements, herbal products and make sure you let your doctor know if you are taking amphotericin B, antifungals, ketoconazole, bromocriptine, cimetidine, HIV protease inhibitors, seizure medication, Phenobarbital, metoclopramide, rifabutin, verapamil or any other medication. Your doctor will need this information to prescribe appropriate dosage of your medication or to monitor for any side effects. Let your doctor know if you are pregnant, plan to become pregnant or breastfeeding. Tell your doctor if you suffer from high cholesterol or triglycerides of liver disease.

It is best to disclose any health conditions and medications to your doctor before taking sirolimus.

Are There Any Side Effects Caused By Sirolimus?

Possible side effects of Sirolimus are:

Headache Constipation Back pain Diarrhea Weight loss Fever Weakness Vomiting Stomach pain

There are other serious side effects which are uncommon, but if you experience pale skin, shortness of breathe of unusual bleeding or bruising you should call your doctor immediately.

The most frequently recommended treatments for pleural mesothelioma patients has been chemotherapy, radiation therapy and surgery or a combination of two or more of these types of treatment and medication. But with sirolimus, this new addition will significantly improve the lives of mesothelioma patients.

These clinical researches are making advancements in the treatment of mesothelioma. Patients suffering from mesothelioma are volunteering to receive the newest development in mesothelioma treatment in the hopes of finding a cure for this disease. We hope that one day there will be a cure for this lethal disease.

Mesothelioma Attorney in California

Mesothelioma Attorney in California

Mesothelioma attorneys help patients to obtain fair compensation if they have the disease due to exposure to asbestos in their workplace. Litigation for mesothelioma cases can extend for long periods, which is why it is very important that you find an attorney. If you are living in California and suffering from the mesothelioma disease then you need an experienced California mesothelioma attorney who can help you to get your fair compensation.

Though Mesothelioma is a serious form of cancer, but it is also unusual. The beginning of this disease starts from the inhalation or ingestion of asbestos particles. Later these particles can penetrate into the lungs, intestines and even heart. Mesothelium is a protective sack that secrets fluids allowing organs to move properly and it is irated by these particles. As a result the mesothelium can develop cancerous tumors which can quickly spread throughout the body. After getting diagnosed of mesothelioma most people live only for around five years after condition develops.

Basically, mesothelioma affects three organs of the body such as lungs, the gastrointestinal tract of the body and the heart. Mesothelioma has been found with different forms. Pleural mesothelioma is one of the most common forms of mesothelioma. The second most common form of mesothelioma is peritoneal mesothelioma which destroys the stomach & intestines. Pericardial mesothelioma is the rarest form of mesothelioma which attacks the membrane lubricates in the heart during circulation.

The victims of this terrible disease have many options available for support even there is no cure for mesothelioma. In order to get support for this dangerous disease, the friends and the family of the mesothelioma patients are recommended to get legal support. As the mesothelioma victims may have many legal options, it is very important that you contact a qualified mesothelioma lawyer in the earliest.

New Mesothelioma Treatments provides all the legal information of California mesothelioma attorneys. You can find here all the local attorneys like California mesothelioma attorney, Mesothelioma attorneys Texas etc.

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A Guide for Mesothelioma Treatments

A Guide for Mesothelioma Treatments

Mesothelioma is a malignant tumor of the mesothelium caused by exposure to asbestos fibers. Because mesothelioma is very hard to control and is known for its late onset of symptoms, the U.S. National Cancer Institute (NCI) is sponsoring clinical trials that are used to find new treatments and efficient ways to use current treatments.

The most popular method is radiation therapy, also called radiotherapy, which involves using high-energy rays to kill cancer cells and shrink tumors. Radiotherapy affects only the treated area during the treatment. The radiation may come from a machine that produces radiation through thin plastic tubes into the area where the cancer cells are found.

A common treatment for the disease is surgery that involves the removal of part of the lining of the chest or abdomen and some of the tissue around it. In case of pleural cancer, a lung may be removed in an operation called a pneumonectomy. In few cases, a part of the diaphragm, the muscle below the lungs that helps with breathing, is also removed.

Anti-cancer drugs are used to kill these malignant cells throughout the body. This is known as chemotherapy and involves injecting the drug into a vein (intravenous or IV). Currently, doctors are also studying the effectiveness of putting chemotherapy directly into the chest or abdomen.

There are various procedures that are used for the treatment of mesothelioma. Generally, the treatment type depends on the location of the cancer, the stage of the disease, the patient’s age, and general health. Pleural effusion that is caused by heart failure or infection can usually be resolved by directing treatment, however, when testing has realized no diagnosis and fluid continues to build or recur, doctors may recommend chest tube drainage and chemical pleurodesis. Chemical pleurodesis is a technique in which a sclerosing agent is used in treatment. It is used to abrade the pleural surfaces producing an adhesion between the parietal and visceral pleurae, which prevents from further effusion by eliminating the space in pleura. Talc is considered the most effective agent for pleurodesis.

Mesothelioma Treatments can be essential for the patients who are suffering from this dangerous disease. In order to get proper mesothelioma treatments the patients should contact with the experienced doctors of reliable treatment centers. New Mesothelioma Treatments is the best treatment center for mesothelioma patients as it has huge lists of mesothelioma treatment centers across the World.

Jeff is an experienced author, he has been writing articles for a reliable Mesothelioma Treatments for more than 4 years. If you need any information or help regarding new mesothelioma treatments please visit our website http://www.newmesotheliomatreatments.com


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Why Mesothelioma Treatment Centers?

Why Mesothelioma Treatment Centers?

Mesothelioma treatment center provide the best treatment for mesothelioma ever known. Firstly, mesothelioma is one of the deadly cancers which is caused by exposure to asbestos related substances. Mesothelioma directly affects the outer protective covering of the lungs, abdomen, and heart. This vital protected covering is referred to as the mesothelium. Peritoneal mesothelioma affects the abdomen while pleural mesothelioma affects the lungs. This is the leading cancer in terms of fatalities, collateral damage is pleural mesothelioma. The asbestos that cause the cancer are mostly airborne fibres. Asbestos is a mineral that occurs naturally and it is mined to be used to produce many products. It has very special properties which make it very suitable for this. Apart from being resistant to heat, it is also fire proof.

Mesothelioma treatment centers offer different traditional ways of healing as well as non traditional methods. The most common traditional ways of treating mesothelioma used are surgery, chemotherapy and radiation. Not all mesothelioma cases have surgery as an option for treatment. The choice of treatment lies on. The doctor who consider a few things before they decide surgery is suitable. If the tumors effect spread beyond its localized area, surgery may not work and it might even do more harm than good. If you qualify for surgery, the doctor will explain to you the various kinds of surgeries depending on the location of the cancer. The treatment is usually undertaken together with chemotherapy and radiation.

This is referred to as ‘multimodal’ treatment and it is used for very sever, size of the tumors, age of the victims. Chemotherapy is the use of combination drugs to get rid of the cancerous cells. It is considered a very weakening therapy because of the strong side effects such as constantly vomiting, high fever, losing hair temporarily, skin infection, loss of appetite etc.

Chemotherapy, the most familiar frequently used, the use of high energy x ray is referred to as radiation and, what it does is to shrink the tumors and the radiation has some side effects which go away in a short while. The non traditional methods include photodynamic therapy. This therapy uses light and it is still in the experimental stage where the cancer cells are specifically destroyed by means of a fiber optic cable. In Mesothelioma treatment center, this treatment but, only those who wish to be part of the experiment can participate.

Get some of the best mesothelioma treatment centers at New Mesothelioma Treatments and get rid of the dangerous mesothelioma disease.

Jeff is an expert author writing articles on Mesothelioma Chemotherapy for several years. If you need any information or help regarding new mesothelioma treatment please contact us.


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New Potentially Successful Mesothelioma Treatment Offered at German Facility

New Potentially Successful Mesothelioma Treatment Offered at German Facility

Copyright (c) 2009 Katie Kelley

Researchers have discovered a new and potentially successful treatment for victims of the deadly lung cancer known as mesothelioma. The treatment is known as chemoembolization and is being offered at a single German facility only. The treatment was recently administered to its first mesothelioma patient, a woman who developed the condition after hugging her father everyday, who was covered in asbestos fibers because of work.

The woman’s cancer has since gone into remission with her tumor having been reduced by more than half, according to BBC news reports.

The method of chemoembolization uses chemotherapy drugs delivered into the “site of a cancer tumor” and “since the chemotherapy drugs are delivered into the tumor, stronger doses of the drugs may be used,” according to research from the Roswell Park Cancer Institute. For mesothelioma cancer patients, a catheter into the lungs may potentially be used to deliver the drugs to the cancer site. Because of the success of the treatment, research is continuing, according to news reports.

Developing Pleural Mesothelioma

Pleural mesothelioma occurs when mesothelioma of the chest develops. The National Cancer Institute (NCI) recently reported that “the pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity.” According to NCI, mesothelioma occurs once cells within the lining of the lungs, known as the mesothelium begin to metastasize. The American Cancer Society (ACS) reported the following as symptoms of pleural mesothelioma:

* pain in the side of the chest

* pain in the lower back

* trouble swallowing

* cough

* fever

* sweating

* fatigue

* weight loss

* hoarseness

* coughing up blood

* swelling in the face, arms

* muscle weakness

* sensory loss

Often symptoms occur within two to three months prior to an initial diagnosis, according to the ACS. It is common that mesothelioma signs and symptoms remain dormant for several years, usually anywhere from 10 to 30 decades.

A number of tests are in existence to determine if a patient has lung cancer and if it is of mesothelioma type or pleural mesothelioma. Additionally, there are blood tests, fluid and tissue as well as imaging tests, which can determine a mesothelioma diagnosis, according to the ACS; they are as follows:

* chest x-rays

* computed tomography scan

* positron emission tomography scan

* magnetic resonance imaging scan

* osteopontin protein blood tests

* thoracoscopy

* tissue biopsy

* laparoscopy

* thoracotomy

* laparotomy

* bronchoscopy

* mediastinoscopy

* immunohistochemistry

* DNA microarray analysis

What to Do Following a Mesothelioma Diagnosis

Once a mesothelioma diagnosis has occurred, there are several actions that can be taken to potentially treat the deadly condition. Unfortunately, mesothelioma is often untreatable. The NCI sponsors clinical trials, which can assist individuals with their mesothelioma diagnosis by offering potentially new mesothelioma treatments that can be administered and studied.

LegalView offers a bountiful mesothelioma information portal found at http://mesothelioma.legalview.com/ . Additionally, individuals can learn about other legal issues including the rare Nephrogenic Systemic Fibrosis side effects as well as what to do if involved in a truck accident incident.


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Treatment Options for Pleural Mesothelioma

Treatment Options for Pleural Mesothelioma

Mesothelioma is a deadly cancer that is directly attributed to asbestos exposure. There are three forms of mesothelioma. These forms are pleural mesothelioma, peritoneal mesothelioma and pericardial mesothelioma. This devastating cancer attacks the mesothelium, or the protective lining of the lungs, abdominal cavity, and heart respectively.


Of the three forms of mesothelioma, pleural mesothelioma is the most common. When asbestos is manufactured, mined or disturbed asbestos fibers are released into the air. Those working with or around asbestos inhale and ingest these fine particles. Over an extended period of time, mesothelioma can take 20 to 60 years to manifest, these asbestos particles can cause normal pleura in the lining of the chest to become abnormal, causing pleural mesothelioma.


Some of the most common symptoms of pleural mesothelioma are persistent cough, shortness of breath, bloody sputum, weight loss, fever, swelling of the face and neck, raspy voice and trouble swallowing. Due to the symptoms of pleural mesothelioma mimicking symptoms of other conditions it may go undiagnosed when the need to start mesothelioma treatment immediately is vital.


After a definitive diagnosis of pleural mesothelioma has been established there are several mesothelioma treatment options that can be undertaken. The type of mesothelioma treatment will depend on several key components. These factors are the extent of the disease, the patient’s history and age, and the location of the tumor.


The most common forms of mesothelioma treatment, for those with pleural mesothelioma, are a pneumonectomy, radiation, chemotherapy, and palliative therapies. One form of mesothelioma treatment is a pneumonectomy, or the removal of the cancerous lung. Depending on the spread of the disease, parts of diaphragm may be removed as well. A pleurectomy may also be used to treat pleural mesothelioma by removing parts of the chest and surrounding tissue. The ability for these procedures to be performed are dependent on the patient’s overall health, spread of the disease, and the amount of asbestos exposure.


Radiation treatment is another form of mesothelioma treatment for those suffering from pleural mesothelioma. Radiation therapy works by placing a radioactive source in the area of disease. The use of radiation has the benefit of destroying cancerous tissue while not exposing healthy cells. This form of mesothelioma treatment can be performed in conjunction with surgery or alone if the individual is to ill for surgery.


Chemotherapy is another common form of mesothelioma treatment for those with pleural mesothelioma. This high toxicity drug is usually administered by injection or in pill form. Some side affects from chemotherapy include nausea, vomiting, hair loss, fatigue and weight loss. This form of mesothelioma treatment is not targeted to a particular area like radiation therapy. Therefore, the drugs used have to make their way through the body to the cancerous area or areas. Unfortunately, this has the disadvantage of exposing healthy tissue to the toxicity of the chemotherapy drugs.


Palliative therapies are also used as a form of mesothelioma treatment for those with pleural mesothelioma. This involves removing excess fluid by needle and suction from the affected areas. Drugs are also used in order to keep fluid accumulation under control.


As additional research is performed on pleural mesothelioma more treatment options may become available. Keeping informed of new mesothelioma treatments is paramount if diagnosed with this devastating disease.

Nick Johnson serves as lead counsel with Johnson Law Group, a law firm with principal offices located in Houston, Texas. Johnson represents plaintiffs with injury cases involving Mesothelioma and Defective Drugs. Contact Nick Johnson at 1-888-311-5522 or visit http://www.johnsonlawgroup.com


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