Posts Tagged ‘Exposure’

Exposure To Asbestos Results In Mesothelioma Cancer

Exposure To Asbestos Results In Mesothelioma Cancer

Mesothelioma cancer is generally found among those people who have been exposed to asbestos. Asbestos is a naturally-occurring material found in the altered industries. These are useful in certain respects but are also harmful to a great extent. In course of mining and manufacturing fibers may be dislodged from the mineral which get attached to the clothes or hair. Over time, the workers inhale the asbestos and this in turn may lead to the development of cancer.

The amount of asbestos inhalation determines the spread of cancer. This disease is also known as asbestos lung cancer. At times, an exposure of only one or two months can result in Mesothelioma. The fibers reach the lungs and progress rapidly. Slowly they move to the lower portion of the lungs and infect the system. However, the cancer can occur after 30-40 years after the exposure to asbestos because it is in this time when the asbestos spreads and reacts in the body. In some cases, it might also occur after 70 years.

The disease occurs generally to persons who are more than 40 years old. However, through out the year only few cases of Mesothelioma are recorded. Still it is better for the persons who are exposed to asbestos to take proper precautions in order to prevent the occurrence of this disease.

A patient is first diagnosed to detect the Mesothelioma cancer. With the help of a biopsy examination, an abnormal tissue is placed under the microscope to detect the disease.

The disease spreads in the body step by step. As early it is detected, the spread of the disease can be prevented. Mesothelioma is generally present in the right or the left side of the pleura and at times also involves the diaphragm with it. This is actually the stage 1 of the disease. In stage 2, the disease invades the chest wall. At times, it can also involve the esophagus, heart or even the pleura on both the sides. In stage 3, the Mesothelioma cancer penetrates through the diaphragm and reaches the abdominal cavity. In the last stage it spreads into the blood streams and the other organs.  

One should know that Mesothelioma occurs more in men than in women. Majority of the types of Mesothelioma cancer is considered to be fatal. The rates of survival in this type of cancer are very rare. However, if early treatment is done, the patient can be made to survive for some more time.

In order to know the measures in order to prevent from asbestos and the consequent Mesothelioma cancer, one should log on to mesotheliomahelp.net. In this site, they would know how they can prevent themselves from asbestos and know that they have the symptoms of Mesothelioma. In this site they would get a ray of hope and they can solve all their doubts related to the disease.


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World Trade Center Asbestos Exposure

World Trade Center Asbestos Exposure

World Trade Center Ruins

 

After “9.11″ terrorist attack, Christine who lives not far away from the original World Trade Center in New York breaks asthma for more than twice per night, His wife also suffers from intolerable headache, finally they have to move out.

 

However, every time on his way back to the old home for fetching letters, he will once again break asthma because of breathing in the metal taste trigger. “I have been suffering from asthma for many years, although sometimes it’s serious, but I had never suffered from so much torture. As long as I smell the weird smell floating from the ruins of the World Trade Center, I would have more asthma”.

 

World Trade Center Asbestos

 

After “9.11″ some environmental experts remind the residents living nearby the World Trade Center that they should pay attention to the harmful gases from the ruins, but New York government denied the fact that the World Trade Center ruins badly affect the surrounding environment. After hearing the experts’ advice, Christine increasingly suspects his condition is worsened by the ruins of the World Trade Center. So he invites an independent agency to test the dust floating around his old home building. The test results prove the dust out of the corridor contains World Trade Center asbestos exceeding 555 times than normal. The test also tells the asbestos fiber in the air has reached a dangerous level.

 

World Trade Center Asbestos Exposure and Mesothelioma

 Plenty of studies on asbestosis approve that individuals who develop the mesothelioma disease after the exposure to asbestos for 40 years or more take account of 90 percent of all cases. There are 75 percent of persons who worked with the toxic mineral for 20-30 years. Those who experienced 10-19 years of exposure take the proportion of 10 to 15 percent. These numbers may also vary based on the level of asbestos individual is exposed to on a daily basis.

Dependent on the Asbestos Exposure

• Individuals with high levels of exposure of a short duration

• Individuals with high levels of exposure of long duration

• Individuals with low levels of exposure of long duration

Please visit the Mesothelioma Rescue official website and know more about the Mesothelioma information and Treatment Options.


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Exposure to Pulmonary Carcinogens and Mesothelioma

Exposure to Pulmonary Carcinogens and Mesothelioma

When pieces of asbestos are inhaled or swallowed, they can lead to life threatening diseases.  To date, over 730,000 people have filed claims for asbestos related injuries in the United States alone. One interesting study that examples the link between exposure and Mesothelioma disease is called, “Analysis of asbestos fibers and asbestos bodies in tissue samples from human lung. An international interlaboratory trial.” by Gylseth B, Churg A, Davis J.M., Johnson N, Morgan A, Mowe G, Rogers A, Roggli V. – Scand J Work Environ Health. 1985 Apr;11(2):107-10.  Here is an excerpt: “Abstract – In order to compare methods of counting asbestos fibers in lung tissue, seven laboratories participated in an interlaboratory trial in which tissue samples from five human lungs were analyzed. In some laboratories, fiber concentrations were assessed with the light microscope and, in others, with either scanning or transmission electron microscopes. Within each laboratory the ranking of the results was similar, but there were marked differences in the absolute values obtained by the different laboratories. It is concluded that the laboratories participating in this trial appear to produce internally consistent results, but there is difficulty in directly comparing results from one laboratory to the next.”

A second study is called, “Reduced Fhit protein expression and loss of heterozygosity at FHIT gene in tumours from smoking and asbestos-exposed lung cancer patients.” By Pylkkanen L, Wolff H, Stjernvall T, Tuominen P, Sioris T, Karjalainen A, Anttila S, Husgafvel-Pursiainen K.  Int J Oncol. 2002 Feb;20(2):285-90.  Here is an excerpt: “Abstract – The FHIT gene, at 3p14.2, has been suggested to form a molecular target to damage induced by human lung carcinogens. We examined aberrant expression of the Fhit protein and allele loss at the FHIT gene in a series of lung cancer cases, mainly of non-small cell carcinoma (NSCLC) histology. We had detailed data on tobacco smoke exposure and occupational asbestos exposure available for the cases. The principal aim of the present study was to investigate whether absent or reduced Fhit expression or FHIT allele loss was associated with exposure to these pulmonary carcinogens. We detected reduced Fhit expression in 62% (33/53) of the cases analysed. Prevalence of allele loss at the FHIT locus was 22% (20/89). Reduced protein expression was common both in the asbestos-exposed (67%) and non-exposed cases (59%); [odds ratio (OR) 1.4, 95% confidence interval (CI) 0.4-4.9]. LOH frequencies differed somewhat between the two groups and were 25% vs. 16%, respectively (OR 1.8; 95% CI 0.5-5.9). Absent or reduced expression was common in smokers, with no significant difference found between current smokers and non-smokers (mainly former smokers) (OR 1.4, 95% CI 0.5-4.5). NSCLCs with squamous cell histology exhibited both aberrant [removed]OR 3.1, 95% CI 0.9-10.3) and allele loss (OR 3.3, 95% CI 0.9-12.7) more frequently than adenocarcinoma. Finally, we found that FHIT allele loss was increased in stage II or more advanced disease (OR 2.5, 95% CI 0.9-7.4), and in poorly differentiated tumours (grade 3, OR 2.6, 95% CI 0.8-8.1). In conclusion, our present data support significance of FHIT inactivation in development of lung cancer.”

A third study is called, “Effects of crocidolite and chrysotile asbestos on cellular uptake and metabolism of benzo(a)pyrene in hamster tracheal epithelial cells.” Environ Health Perspect. 1983 September; 51: 331 by B. T. Mossman, A. Eastman, J. M. Landesman, and E. Bresnick.  Here is an excerpt: “Abstract – The incidence of bronchogenic carcinoma is increased substantially in asbestos workers who smoke. We used several approaches to determine possible mechanisms of synergism at the cellular level between asbestos and the polycyclic aromatic hydrocarbon (PAH), benzo(a)pyrene (BaP), a chemical carcinogen in cigarette smoke. Specifically, we hypothesized that cellular uptake and metabolism of BaP might be facilitated when the hydrocarbon was coated on asbestos. In addition, we were interested in whether asbestos, alone or in combination with BaP, caused single strand breakage of DNA in epithelial cells of the airway. UICC reference samples of crocidolite and chrysotile were coated with 3H-BaP before their addition to monolayers of hamster tracheal epithelial cells. In comparative studies, 3H-BaP at identical amounts was added to cells in culture medium. At intervals thereafter, uptake of BaP by cells was documented by scintillation spectrometry and by autoradiography. In addition, cells and media were assayed by use of high pressure liquid chromatography (HPLC) to demonstrate the water-soluble metabolites of BaP. The integrity of DNA was monitored by alkaline elution at intervals after exposure of tracheal cells to various concentrations of asbestos, BaP and BaP-coated asbestos. A rapid transfer of BaP to cells occurred after addition of BaP-coated asbestos to cultures. When BaP was adsorbed to both types of fibers before their addition to cultures, 70% of the total BaP introduced entered the cell within 1 hr; 50% remained intracellular after 8 hr.”

If you found any of these studies interesting, please read them in their entirety.  We all owe a great deal of thanks to the people who are researching these important issues.

Monty Wrobleski is the author of this article, for more information please visit the following links Nephrogenic Systemic Fibrosis,

Nephrogenic Systemic Fibrosis Lawyer,

Mesothelioma Attorneys


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Asbestos Exposure, Malignant Lung Cancer – California Lawyer

kazanvideo.com Asbestos exposure can cause malignant Lung Cancer and other diseases in the California area. These diseases cause victims and their families pain, suffering, and medical expenses. If you or a loved one has been exposed to Asbestos, or is at risk for malignant lung cancer or Mesothelioma, we can help. Find the information you need at our website, or call today 877.622.5246 for a no cost evaluation.
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Mesothelioma Info on Asbestos Exposure Risk in San Diego

www.KazanVideo.com Those at mesothelioma asbestos exposure risk in San Diego can turn to Kazan Law in the pursuit of justice. Our pioneer asbestos lawyers ensure that mesothelioma patients neednt suffer alone. Kazan will fight to get you comp pay if you have mesothelioma peritoneum. To learn about mesothelioma asbestos exposure risk in San Diego, visit our website or call 877.622.5246.

Asbestos Exposure Threatens Schools, Prisons

Asbestos Exposure Threatens Schools, Prisons

Asbestos contamination has led to several temporary closures of schools and prisons nationwide in the last year, causing many to be concerned about the health and safety of those who have spent time within the walls of these American institutions.

Asbestos can cause a slew of dangerous health problems, including mesothelioma, a rare but deadly form of lung cancer. Even the slightest exposure can have life-long and debilitating side effects far into the future. The initial exposure is often difficult to pin-point. Protecting individuals from asbestos is necessary and vital because mesothelioma and other health problems can take upwards of 30 to 40 years to manifest.

An insurgence of mesothelioma lawsuits as occurred as more asbestos contaminants have been discovered in schools, prisons and other highly trafficked buildings, since mesothelioma and other side effects of asbestos are preventable.

The most recent school closure outside of Boulder, Colo. resulted in a school-wide evacuation and class cancellation until the risk could be evaluated. During a million renovation, asbestos was suspected to be found in Niwot High School, a high school outside of Boulder, Colo.

Asbestos was commonly used in the construction of older buildings before it was outlawed, however it is often not discovered until costly renovations years later. Removal is a time-consuming and costly process that should only be conducted by a license professional to avoid exposure. A school district in Ohio, among other districts has requested additional assistance to pay for the costly asbestos removal. Because many of these renovations are reliant on taxpayer approval, many of these costly projects are unable to find the additional funds necessary to remove the asbestos.

Demolition of asbestos-contaminated buildings can cause those involved to suffer from the after effects, as illustrated by the 9/11 attacks on the World Trade Center. Many lawsuits and health-related problems have been reported among the emergency personnel who responded, dubbing the side effects as the “World Trade Center Cough.” The toxic Ground Zero dust contained asbestos fibers and other contaminants as illustrated as the lack of improved lung function among the responding EMTs and firefighters. It is clear that controlled asbestos removal is a vital precaution, although more research is needed to determine the life-long effects.

Luckily, many of the school and prison closures have been temporary, with limited if any exposure to students and staff. However, those who feel they have been exposed, or who have felt the side effects of asbestos exposure should contact a mesothelioma attorney to discuss the possibility of a mesothelioma lawsuit.

Learn more about mesothelioma law and finding a potential mesothelioma lawyer at http://mesothelioma.legalview.com/. Get up-to-date information, treatment options and more at http://legalview.info/ .


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