Posts Tagged ‘Pleural’

Pleural Mesothelioma

Pleural Mesothelioma

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The most common type of is Pleural Mesothelioma. It accounts for 70 to 75% of total patients suffering from mesothelioma. The cancer affects the pleural mesothelium of the lungs due to asbestos accumulation.

Inhalation of asbestos cause collection of these fibers inside the lungs and these penetrate the walls of mesothelium and enter the pleura due to a small microscopic size. While migrating from the mesothelium to pleura it damages the mesothelium.

Asbestos invade the pleural cavity forming cancers in the mesothelium and damaging it. The cancer tissues formed will thicken the fluid of the pleura and so inhibiting the proper lung movements.  These tumors can constrict the lungs and generate pressure on the ribcage and other organs in some cases as well thus cause severe pains in these organs.
Due to the lungs involvement in blood oxygenation the cancers of lungs can generally spread to other parts of the body through the blood stream. This renders the pleural mesothelioma malignant.

The most common problem that is related to the diagnosis of pleural mesothelioma is that it is often confused with less serious and deadly diseases as common cold, pneumonia, flu, whooping cough and laryngitis. Sometimes there are no symptoms present in pleural mesothelioma.

The mutation that asbestos fibers cause the to develop cancers is studied by scientists and doctors. They still are unaware of the causes of such mutations. It is believed that even one single asbestos fiber is capable of causing this mutation that ends up in mesothelioma. The increased number of cases that are being reported has been helpful for these researchers to study further about this disease.

An asbestos particle generally takes a long time to turn into cancerous tissue and that to up to 30 to 40 years after exposure. Therefore the spotting of the cancer is still difficult in early stages as most cases develop in the alveolar sac of the lungs.

As there still is no specific cure for mesothelioma, doctors try to diagnose the disease as early as possible so as to relieve the sufferings of the mesothelioma patients. This will help in prolonging and improving the life of the mesothelioma patient. The treatment opportunities are all dependant on the extent of the condition and the disease progression.
The treatment options in case of the pleural mesothelioma generally include surgery, chemotherapy and radiations

Surgery is done to remove a part or complete lung to cut off the cancerous tissue. This will prevent the cancer tissue from further spreading in the lungs and to the other parts of the body. In some cases the fluid is needed to be removed from the lungs. But in extreme cases the entire lung is needed to be removed.

High doses of radiation are often used to treat these pleural cancers. The radiation technique uses high energy waves that kill the malignant cancer cells. Cancer cells along with the healthy ones are killed therefore causing peripheral health problems as well.
Anti cancer drugs are also used to treat these . Here strong drugs are pumped into the tumors or taken orally that can inhibit the cancer growth and spread in the lungs or body. But these like radiations can pose other serious health problems as well.
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pleural mesotheloma

pleural mesotheloma

The Pleural Mesothelioma is one of the most common forms of mesothelioma that exist, and in the malignant form it is the direct consequence of the exposure to asbestos fibers. One can obtain beginning tumors with the pleural mesothelioma, but its malignant form is by means far the most common. The gasping in of the asbestos fibers is the cause that puts those ones that works unprotected with the asbestos at maximum risk, and these risks could be heightened through smoking and also by the exposure to this risky fiber.

Pleural mesothelioma mostly attacks the parts of the lungs and the whole respiratory areas of the human body. These are a form of cancer and mainly attack the cells of the lining known as pleura of the ribs and the lungs. With the other forms of pleural mesothelioma, the various symptoms could take more than twenty to thirty years or sometimes longer. There are a numerous of common symptoms for the pleural mesothelioma, and like the common peritoneal mesothelioma, they might appear as very non-specific and might be put downward to a amount of common illness or diseases. The extended latency period connected with this mesothelioma is previously the cause of delay, except the type of various symptoms that are associated with this illness may cause even more delay, even while the inception begins. With no prior awareness that one have worked with the exposure of asbestos and are therefore the elevated risk patient where the pleural mesothelioma is concerned with, ones doctor might end up trying for the wide variety of the other diseases such as the pneumonia. These wastes to a large amount need time, and so it is vital that one not only maintain his eyes open for some of the connected symptoms but moreover inform ones doctor of his past account of working with the asbestos. All armed with information, the doctor of medicine could then start in running suitable tests.

Some of the common symptoms that are associated with the pleural mesothelioma are: the persistent coughing; facial swelling, difficulty in swallowing; fever, weight loss; rasping; and in some it also extends up to coughing up blood. Some of the patients may also go through the shortness of breath, whether they are in sleep or active. This may be caused due to the thickening of the pleura which is formed due to the increase of the tumor. As much the pleura get thicker, the reduced amount of space the lungs will have to function up properly, therefore the breathing start on to be affected.

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Pleural Mesotheloma- Facts you should know

Pleural Mesotheloma- Facts you should know

Mesothelioma is the commonest primary tumor of the pleura.There are two main types;

1]the localized mesothelioma{benign and malignant types} 2]the diffuse malignant mesothelioma

Causes

There is a strong correlation between asbestos exposure and the development of mesothelioma,although a history of exposure is not always obtainable in patients who have mesothelioma.There are 2 types of asbestos fibres based on crystalline structure;a-serpentine{chrysolite}and b-amphibole.

Included within the amphibole are amosite,tremolte,crocidolite and anthophyllite.The most harmful is the crocidolite or better known as blue asbestos.

Localised Bening Mesothelioma

These characteristically arise from the inner layer of the pleura

Symptoms and signs;

-chest pain -shortness of breath -most of the times there are no symptoms{asymptomatic},these tumors are usually discovered on routine chest x-ray -hypoglycemia {low blood sugar}is sometimes associated Treatment

Surgery is the main stay of treatment,the tumor is removed by the surgeon and reccurence is rare and when it happens transition to malignant form of tumor should be suspected.

Localised Malignant Mesothelioma

Symptoms and Signs;

-chest pain -cough -fever -shortness of breath

Treatment

Surgery is also the treatment of choice,although prognosis is very poor

Diffuse Malignant Mesothelioma

This type of mesothelioma can arise form any part of the pleura and often extend into the peritoneum as well as into the ribs and chest wall{peritoneal mesothelioma and pericardial mesothelioma}.It also spreads commonly to the liver, brain and adrenal glands.Histologically malignant mesothelioma have both fibrous{sarcomatous mesothelioma}and epithelial{papillary}components.

Investigations

-CT scan of the chest is extremely useful in diagnosing the extent of the tumor. -Needle biopsy{the surgeon inserts a special needle into the pleura to take samples of the tumor which is taken to the laboratory to see under the microscope}of the pleura is a must.
-Pleural fluid is aspirated and taken to the lab for microscopic examination.

Staging of Malignant Pleural Mesothelioma

-Stage 1:Involvement of ipsilateral pleura and lungs{affecting just one lung either left or right lung}
-Stage 2-Involvement of chest wall,mediastinum{structure at the middle of the heart},pericardium or contralateral{opposite side}pleura
-Stage 3-Distant blood spread into other organs eg brain,adrenals

Treatment

Treatment is discouragingly ineffective and survival rarely longer than 2 years with an average of 10-14 months.In selected cases with stage 1 a radical sugery-pleuropneumonectomy{removal of lung and pleura} may be effective,but long term survival is rare.Primary radiation therapy may be used also. Combination chemotherapy using either single agent or combination protocols have also been used but the outcome remains dismal.

Bello kamorudeen is an health worker and author of several mesothelioma articles.For more information on types of mesothelioma go to http://www.mesotheliomacorner.blogspot.com


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Find More Mesothelioma Staging Articles

Pleural Mesothelioma Facts

Pleural Mesothelioma Facts

Mesothelioma is the commonest primary tumor of the pleura. There are two main types;
1] the localized mesothelioma{bening and malignant types}
2] the diffuse malignant mesothelioma

Causes
There is a strong correlation between asbestos exposure and the development of mesothelioma, although a history of exposure is not always obtainable in patients who have mesothelioma. There are 2 types of asbestos fibers based on crystalline structure; a-serpentine {chrysolite} and b-amphibole. Included within the amphibole are amosite, tremolte, crocidolite and anthophyllite. The most harmful is the crocidolite or better known as blue asbestos.

Localised Bening Mesothelioma

These characteristically arise from the inner layer of the pleura
Symptoms and signs;
-chest pain
-shortness of breath
-most of the times there are no symptoms {asymptomatic}, these tumors are usually discovered on routine chest x-ray
-hypoglycemia {low blood sugar} is sometimes associated

Treatment
Surgery is the main stay of treatment, the tumor is removed by the surgeon and recurrence is rare and when it happens transition to malignant form of tumor should be suspected.

Localized Malignant Mesothelioma
Symptoms and Signs;
-chest pain
-cough
-fever
-shortness of breath
Treatment
Surgery is also the treatment of choice, although prognosis is very poor

Diffuse Malignant Mesothelioma
This type of mesothelioma can arise form any part of the pleura and often extend into the peritoneum as well as into the ribs and chest wall {peritoneal mesothelioma and pericardial mesothelioma}. It also spreads commonly to the liver, brain and adrenal glands. Histologically malignant mesothelioma have both fibrous {sarcomatous mesothelioma} and epithelial {papillary} components.

Investigations
-CT scan of the chest is extremely useful in diagnosing the extent of the tumor.
-Needle biopsy {the surgeon inserts a special needle into the pleura to take samples of the tumor which is taken to the laboratory to see under the microscope} of the pleura is a must.
-Pleural fluid is aspirated and taken to the lab for microscopic examination.
Staging of Malignant Pleural Mesothelioma
-Stage 1:Involvement of ipsilateral pleura and lungs {affecting just one lung either left or right lung}
-Stage 2-Involvement of chest wall, mediastinum {structure at the middle of the heart}, pericardium or contralateral {opposite side} pleura
-Stage 3-Distant blood spread into other organs eg brain, adrenals

Treatment
Treatment is discouragingly ineffective and survival rarely longer than 2 years with an average of 10-14 months. In selected cases with stage 1 a radical surgery-pleuropneumonectomy may be effective, but long term survival is rare. Primary radiation therapy may be used also. Combination chemotherapy using either single agent or combination protocols have also been used but the outcome remains dismal.

Bello kamorudeen.To learn more on Pleural Mesothelioma go to http://www.mesotheliomacorner.blogspot.com


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Pleural Mesothelioma Malignant Pleural Asbestos Cancer

Malignant Pleural Mesothelioma is a rare type of cancer that develops from Asbestos exposure. The fibers then lodge in the body and cause malignant cancer cells to develop in the lining of the lungs. Symptoms for malignant Pleural Mesothelioma may not present themselves for decades. If you may have been exposed to Asbestos in the past, it is vital to inform your doctor. Learn more in this video and visit kazanvideo.com or visit 877.622.5246.
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Treatment Options for Pleural Mesothelioma

Treatment Options for Pleural Mesothelioma

Mesothelioma is a deadly cancer that is directly attributed to asbestos exposure. There are three forms of mesothelioma. These forms are pleural mesothelioma, peritoneal mesothelioma and pericardial mesothelioma. This devastating cancer attacks the mesothelium, or the protective lining of the lungs, abdominal cavity, and heart respectively.


Of the three forms of mesothelioma, pleural mesothelioma is the most common. When asbestos is manufactured, mined or disturbed asbestos fibers are released into the air. Those working with or around asbestos inhale and ingest these fine particles. Over an extended period of time, mesothelioma can take 20 to 60 years to manifest, these asbestos particles can cause normal pleura in the lining of the chest to become abnormal, causing pleural mesothelioma.


Some of the most common symptoms of pleural mesothelioma are persistent cough, shortness of breath, bloody sputum, weight loss, fever, swelling of the face and neck, raspy voice and trouble swallowing. Due to the symptoms of pleural mesothelioma mimicking symptoms of other conditions it may go undiagnosed when the need to start mesothelioma treatment immediately is vital.


After a definitive diagnosis of pleural mesothelioma has been established there are several mesothelioma treatment options that can be undertaken. The type of mesothelioma treatment will depend on several key components. These factors are the extent of the disease, the patient’s history and age, and the location of the tumor.


The most common forms of mesothelioma treatment, for those with pleural mesothelioma, are a pneumonectomy, radiation, chemotherapy, and palliative therapies. One form of mesothelioma treatment is a pneumonectomy, or the removal of the cancerous lung. Depending on the spread of the disease, parts of diaphragm may be removed as well. A pleurectomy may also be used to treat pleural mesothelioma by removing parts of the chest and surrounding tissue. The ability for these procedures to be performed are dependent on the patient’s overall health, spread of the disease, and the amount of asbestos exposure.


Radiation treatment is another form of mesothelioma treatment for those suffering from pleural mesothelioma. Radiation therapy works by placing a radioactive source in the area of disease. The use of radiation has the benefit of destroying cancerous tissue while not exposing healthy cells. This form of mesothelioma treatment can be performed in conjunction with surgery or alone if the individual is to ill for surgery.


Chemotherapy is another common form of mesothelioma treatment for those with pleural mesothelioma. This high toxicity drug is usually administered by injection or in pill form. Some side affects from chemotherapy include nausea, vomiting, hair loss, fatigue and weight loss. This form of mesothelioma treatment is not targeted to a particular area like radiation therapy. Therefore, the drugs used have to make their way through the body to the cancerous area or areas. Unfortunately, this has the disadvantage of exposing healthy tissue to the toxicity of the chemotherapy drugs.


Palliative therapies are also used as a form of mesothelioma treatment for those with pleural mesothelioma. This involves removing excess fluid by needle and suction from the affected areas. Drugs are also used in order to keep fluid accumulation under control.


As additional research is performed on pleural mesothelioma more treatment options may become available. Keeping informed of new mesothelioma treatments is paramount if diagnosed with this devastating disease.

Nick Johnson serves as lead counsel with Johnson Law Group, a law firm with principal offices located in Houston, Texas. Johnson represents plaintiffs with injury cases involving Mesothelioma and Defective Drugs. Contact Nick Johnson at 1-888-311-5522 or visit http://www.johnsonlawgroup.com


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