Posts Tagged ‘Treatments’

Mesothelioma Cancer Researchers Eye Biomarkers for Treatments

Mesothelioma Cancer Researchers Eye Biomarkers for Treatments

Copyright (c) 2008 Katie Kelley

A study from the Department of Molecular Pathology at the Polytechnic University of Marche in Acona, Italy recently found that biomarkers within the body may offer early warning signs for mesothelioma victims.

The study focused on biomarkers of mesothelioma cancer and found that biomarkers often form before mesothelioma cancer symptoms appear, which may offer early warnings and potentially a successful treatment for mesothelioma cancer patients, according to the study which was published in a June issue of Mutation Research.

Studying Biomarkers to Help Mesothelioma Treatment

Biomarkers are a type of “biochemically expressed substance” similar to a protein, according to a news report on the study. An effort is being collaborated on by the International Cancer Biomarker Consortium (ICBC) to better address biomarkers as indicators of cancer types such as mesothelioma.

The large-scale effort is similar, according to the ICBC, to the Human Genome Project and uses an array of researchers from around the world to assist in studying the use of the the biomarkers. The Polytechnic study followed 119 individuals who had been previously exposed to asbestos; of these individuals, all exhibited increased numbers of biomarkers compared to individuals who were not exposed to asbestos.

What is Mesothelioma Cancer

Mesothelioma is a type of lung cancer that can develop after an individual is exposed to asbestos fibers or asbestos dust. After an individual is exposed to asbestos fibers, they may begin to develop cancerous cells on the interior lining of the lung. The cancer is often described as one of the only preventable forms of cancer especially since individuals are still being exposed to asbestos in America through improper cleanup and disposal methods. Asbestos can be found presently in an array of buildings including apartment complexes, homes, elementary schools, universities, hospitals and offices.

Unfortunately, individuals continue to be exposed to asbestos fibers because of its existence in many products implemented throughout the country, and because it is too costly to remove all asbestos by the Environmental Protection Agency (EPA), many remain at risk. Additionally, because mesothelioma cancer usually remains dormant for years, it becomes increasingly difficult to diagnose and to successfully treat.

Finding Help for Asbestos Related Conditions Like Mesothelioma

It is important that individuals who may have been exposed to asbestos to contact a medical professional immediately to assess and potentially diagnose their condition. If mesothelioma cancer is diagnosed early on a mesothelioma victim has a better chance of decreasing the risks of fatality commonly associated with the cancer.

In addition to contacting a medical professional it may also be important to contact an experienced mesothelioma attorney to learn about developing a mesothelioma lawsuit, which may result in receiving monetary compensation to pay for expensive mesothelioma medical bills.

The latest on mesothelioma can be found at http://www.mesothelioma-law-now.com or at http://www.LegalView.com/. Additionally, victims of truck accident injuries or those needing an Avandia attorney can also use the site to better understand their situation and how to overcome their legal problems.


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Alimta and Cisplatin for Mesothelioma Treatments

Alimta and Cisplatin for Mesothelioma Treatments

The Food and Drugs Administration (FDA) have approved a combination of Alimta and Cisplatin for mesothelioma treatments, and other asbestos-associated diseases. The happens to be the first and only drug that is proved to help treat mesothelioma patients having any asbestos-associated disease approved by the FDA. Alimta was endorsed to be used with cisplatin, which is an approved chemotherapy agent good for malignant mesothelioma treatments, a deadly tumor of the lung lining, in mesothelioma patients who do not want to undergo surgery. One of the most lethal, painful, and devastating cancers a person can have is malignant mesothelioma. There are about 10,000 and 15,000 mesothelioma patients annually diagnosed with malignant mesothelioma in the world, and it increases greatly every year. Several people do not even know that they have malignant mesothelioma until it has gotten to a severe and advanced stage, whereby mesothelioma treatments options of surgery or radiation are not necessary. Alimta/cisplatin have really proven different. There was a comparison of this combination with cisplatin alone with around 448 mesothelioma patients from 19 nations – the biggest trial till date among mesothelioma patients having malignant mesothelioma. The results shown was that the total survival rate was 30% increased (about Alimta/cisplatin was used for 12.1 months compared to 9.3 months for cisplatin alone), and about 50.3% of mesothelioma patients undergoing Alimta/cisplatin treatment lived a year after in comparison to 38.0% who had only cisplatin. It has been proved for the first time that chemotherapy assists mesothelioma patients with malignant mesothelioma extend their lives, which is something to count for. Furthermore, research have also shown that there was an lung functionality improvement when the Alimto/Cisplatin was used, compared to the use of Cisplatin alone. However, there are some vital safety information. There are hematolgoic and non-hematologic side effects related to the use of Alimta, and they are anaemia, neutropenia, nausea, thrombocytopenia, vomiting, diarrhea, fatigue, pain, and skin rash. In order to decrease the severity of the side effects, all mesothelioma patients using Alimta must take a dose of folic acid and intramuscular injections of vitamin B12 daily.

My favourite blog – Mesothelioma Portal


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Treatments for mesothelioma cancer and the treatment options available

Treatments for mesothelioma cancer and the treatment options available

The prognosis for mesothelioma is dependent on a number of factors such as how advanced the stage of cancer is, where the cancer originated, the patient’s medical history etc. Patients diagnosed with mesothelioma are told that they can expect to live for another 10 to 12 months as the stage is very advanced by the time mesothelioma is detected in most cases. However cancer treatment centers often have better statistics than this. The conventional options for treating mesothelioma are surgery, radiation therapy and chemotherapy. Sometimes two or all three of these options are combined for best possible results.

Thorascopy allows a doctor to examine the pleural cavity and to perform as many biopsies as he can to ensure the stage and rate of growth of the malignance. In this process, the fluids clogging the cavities can also be cleared so as to give the patient some kind of temporal relief. Via this method, the tumours can be tested as well and all basic information regarding the kind of mesothelioma can be gathered.

An alternative to thorascopy is video assisted thoracic surgery. In this case the cuts are not as lengthy as in the first case. Smaller incisions are made and the same process can be performed with the help of camera which gives a larger picture of what the state of the interior is like. Some doctors also use the method of mediastinoscopy or laproscopy. Incases where images suggest that tumours are a rather intrinsic involvement in a case of mesothelioma, either of these two procedures can be adopted.

Then there options for treating mesothelioma that are palliative by nature. In this case, the disease itself is not aggressively treated as that is believed by some experts to worsen the situation. The first of this kind is chest tube drainage. Since fluid congestion is a common symptom of mesothelioma, this process helps to empty this unwanted fluid with the help of a catheter and empty the cavity of the patient. There is also the option of pleurectomy which is an option when surgery is a complete no no. in this case only the tumours ar removed and the patient is left to recuperate on his own thereafter.

The last of these unconventional treatment options include potentially curative methods. These procedures help to cure in particular without engaging in any severe form of surgery. Along with a combination of therapies, counseling sessions are provided which helps the individual the develop a greater self esteem and fight for the longest days that he can as mesothelioma being detected in its stage that it usually is detected in honestly leaves very little options to avail of by the medical experts. The state of health of patients usually at the time of diagnosis disables the pursuing of any particular surgical treatment as the body is not fit to battle the severe doses of chemotherapy and radiation therapy.

Speak to a medical expert to know more about these available measures as which will suit you best only they can tell.

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The Mesothelioma Research Foundation of America has a mission: fund research that will lead to the quickest cure for mesothelioma. Mesothelioma is a cancer of the lining of the lungs caused by asbestos exposure. This cancer disease had few treatment options until this Foundation and Dr. Parkash Gill’s work created better treatment options. Today, the future looks more hopeful for additional improved treatment options available to those stricken by this cancer.
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Treatments of Mesothelioma Cancer

Treatments of Mesothelioma Cancer

There are treatments for all patients with malignant Mesothelioma. However, the treatment option that is chosen for a particular patient depends on a number of factors such as the location of the cancer, the stage of the disease, patient’s age and general health, the extent of the damage, etc. treatment is generally of three kinds,

1. Surgery in which case the cancerous portion is removed from the body.
2. Radiation therapy (using x-rays or other high-energy rays to kill cancer cells).
3. Chemotherapy (using drugs to fight the cancer).

Surgery
Surgery is the physical way of treating Mesothelioma in which the cancerous cells are physically removed. Surgery is a common way to treat malignant Mesothelioma. The doctor may remove part of the lining of the chest or abdomen and some of the tissue around it. Sometimes, if the cancer has spread widely, a lung can be totally removed in a surgical procedure called a pneumonectomy. Along with the lung, part of the diaphragm, is also sometimes removed, diaphragm is the muscle below the lungs that helps with breathing. This will temporarily solve the problem of difficulty in breathing.

Radiation Therapy
In radiation therapy high-energy x-rays are used to kill cancer cells and shrink tumors. There are two kinds of radiation therapy, external radiation therapy and internal radiation therapy. When the radiation comes from a machine outside the body it is called external radiation therapy. When materials that produce radiation, are put inside the body through thin plastic tubes in the area where the cancer cells are found, it is called internal radiation therapy.

To relieve symptoms and control pain, the doctor may use a needle or a thin tube to drain fluid that has built up in the chest or abdomen. The procedure for removing fluid from the chest is called thoracocentesis. Removal of fluid from the abdomen is called paracentesis. Drugs may be given through a tube in the chest to prevent more fluid from accumulating. Radiation therapy and surgery may also be helpful in relieving symptoms.

Chemotherapy
Chemotherapy uses drugs to kill cancer cells. Chemotherapy may be taken by pill, or it may be put into the body by a needle in the vein or muscle. Chemotherapy is called a systemic treatment because the drug enters the bloodstream, travels through the body, and can kill cancer cells throughout the body. In Mesothelioma, chemotherapy may be put directly into the chest (intrapleural chemotherapy).

Treatment options for people with Mesothelioma have improved significantly. This is more so in cases where the diagnosis has been early and treatment has been aggressive. Many people are treated with a combination of the above-discussed therapies and this is known as multimodal therapy. Mesothelioma is a fatal disease and so far no cure has been found for the disease. However, treatments can reduce pain and improve lung function. Easily administered pain killers are now used to control pain.

Rob Mellors helps people find out about mesothelioma and mesothelioma treatment


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Your Guide to Mesothelioma Treatments

Your Guide to Mesothelioma Treatments

Mesothelioma treatment relates relieving or curing the deadly disease called mesothelioma. Mesothelioma is serious disease that affects the lining of lungs, abdominal organs or heart. Mesothelioma can be of two types, either benign or malignant. Mesothelioma treatment, for an individual suffering from benign mesothelioma, is surgery. However, in case of malignant mesothelioma scientists could not find any established mesothelioma treatment to cure the patient fully.

Types of Mesothelioma Treatment
Mesothelioma treatment options available today are radiation, chemotherapy, radical surgery and/or combination of all these treatments. During surgery, either a part of tumor or the whole tumor is removed. In some cases, a portion of the normal tissue surrounding the area is also removed along with the tumor.

Mesothelioma treatment, in which the doctors try to cure the patient with drugs, is known as chemotherapy. As the mesothelioma cancer is a rare disease, very little information is available regarding the effects of different drugs on different patients. Adriamycm, (doxorubicin), Cytoxan, (cyclophosphamide), 5-fluorouracil and 5-azacytidine are some of the drugs that have shown good results and a response rate of 0 to 35 % when tried on mesothelioma patients. Some other effective drugs for mesothelioma treatment are cisplatin, high dose methotrexate, interferon, anthracycline analogues and vinblastine. The National Cancer Institute is sponsoring further studies the effectiveness of these and other drugs by funding many clinical centers.

Radiation is another option of mesothelioma treatment that is more helpful in reducing the pain rather than curing the disease itself. Because of the severity of the disease, standard dose of 6,000 rads of radiation has very little effect on mesothelioma patients. In limited cases, some benefit is observed when patient is treated with aggressive high dose radiation. Use of radioactive compounds on diseased tissue has also shown some positive results with the individuals diagnosed early on. Patients of pleural mesothelioma survived for over 24 months when radioactive colloidal gold (Au 198) was placed between the two pleural membranes. Scientists are hopeful that radioactive chromic phosphate, p32 can be used as an effective mesothelioma treatment. This might increase the survival period of patients suffering from peritoneal mesothelioma.

Like the treatment of other cancers, mesothelioma treatment also has its side effects. Nausea and vomiting are some minor problems associated with radiation therapy and chemotherapy that could be controlled with medicines. However, suppression of bone marrow is a serious short-term side effect that may cause WBC, RBC and platelets counts to go down. Such patients may become susceptible to bleeding and infection and may require antibiotic therapy or any other supportive care.

Mesothelioma treatment can be a very expensive and lengthy procedure. However, the patients suffering from mesothelioma cancers can seek compensation for mesothelioma treatments. They can file lawsuits against the individuals or organizations responsible for causing asbestos exposure.

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